Endocrine Abstracts

Surgery and radiotherapy are used in the treatment of pituitary tumours. Treatment regimens for pituitary tumours vary depending upon perceived risks of radiotherapy.The aim of the study was to determine whether pituitary disease itself, surgery or radiotherapy, affect cognitive function. This was a controlled prospective design. Two groups were studied, transphenoidal adenomectomy (TSA) pituitary patients (active), and functional endoscopic sinus surger...

Between March 1998 and October 2002, 62 patients requiring trans-sphenoidal pituitary surgery (PS) and 36 patients requiring endoscopic sinus surgery (controls, C) were recruited. Patients were aged 18–65 years and had not had previous surgery or radiotherapy to the brain. The mean ages (p>0.05) and genders (p>0.05) of the two groups were similar 47 years, 41% male (PS) compared with 43 years, 39% male (C). Baseline IQ of the two groups was also similar, 101&#177...